With VirtualBox Appliances you don’t need to install and setup your box for your specific needs. This has already been done.
Instead you choose a box that already includes what you need.
As an example I have been starting working on Drupal development using such a box.
Here are lists of boxes you can use as starter images
And here are some selected boxes
- Windows clones
- Various Appliance formats: http://www.turnkeylinux.org/docs/builds
- Checking out Xen Hypervisor: https://rasor.wordpress.com/2012/12/12/xen-hypervisor/